sd1.040 Fab in complex with SARS-CoV-2 Spike 2P glycoprotein
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8d48
Q-score: 0.449
Bianchini F, Crivelli V, Abernathy ME, Guerra C, Palus M, Muri J, Marcotte H, Piralla A, Pedotti M, De Gasparo R, Simonelli L, Matkovic M, Toscano C, Biggiogero M, Calvaruso V, Svoboda P, Cervantes Rincon T, Fava T, Podesvova L, Shanbhag AA, Celoria A, Sgrignani J, Stefanik M, Honig V, Pranclova V, Michalcikova T, Prochazka J, Guerrini G, Mehn D, Ciabattini A, Abolhassani H, Jarrossay D, Uguccioni M, Medaglini D, Pan-Hammarstrom Q, Calzolai L, Fernandez D, Baldanti F, Franzetti-Pellanda A, Garzoni C, Sedlacek R, Ruzek D, Varani L, Cavalli A, Barnes CO, Robbiani DF
Sci Immunol (2023) 8 pp. eade0958-eade0958 [ Pubmed: 36701425 DOI: doi:10.1126/sciimmunol.ade0958 ]
- Sd1.040 fab heavy chain, sd1.040 fab light chain (Complex from Homo sapiens)
- Sd1.040 fab in complex with sars-cov-2 spike 2p (79 kDa, Complex)
- Sd1.040 fab light chain (24 kDa, Protein from Homo sapiens)
- Sd1.040 fab heavy chain (24 kDa, Protein from Homo sapiens)
- Spike glycoprotein (139 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 7upw
Q-score: 0.464
Luo S, Zhang J, Kreutzberger AJB, Eaton A, Edwards RJ, Jing C, Dai HQ, Sempowski GD, Cronin K, Parks R, Ye AY, Mansouri K, Barr M, Pishesha N, Williams AC, Vieira Francisco L, Saminathan A, Peng H, Batra H, Bellusci L, Khurana S, Alam SM, Montefiori DC, Saunders KO, Tian M, Ploegh H, Kirchhausen T, Chen B, Haynes BF, Alt FW
Sci Immunol (2022) 7 pp. eadd5446-eadd5446 [ Pubmed: 35951767 DOI: doi:10.1126/sciimmunol.add5446 ]
- Spike glycoprotein (144 kDa, Protein from Severe acute respiratory syndrome coronavirus)
- Three rbd-down state of sars-cov-2 d614g spike in complex with the sp1-77 neutralizing antibody fab fragment (650 kDa, Complex)
- Spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus)
- Sp1-77 fab heavy chain (49 kDa, Protein from Homo sapiens)
- Sp1-77 fab light chain (23 kDa, Protein from Homo sapiens)
- Sp1-77 fab heavy chain, sp1-77 fab light chain (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7upx
Q-score: 0.513
Luo S, Zhang J, Kreutzberger AJB, Eaton A, Edwards RJ, Jing C, Dai HQ, Sempowski GD, Cronin K, Parks R, Ye AY, Mansouri K, Barr M, Pishesha N, Williams AC, Vieira Francisco L, Saminathan A, Peng H, Batra H, Bellusci L, Khurana S, Alam SM, Montefiori DC, Saunders KO, Tian M, Ploegh H, Kirchhausen T, Chen B, Haynes BF, Alt FW
Sci Immunol (2022) 7 pp. eadd5446-eadd5446 [ Pubmed: 35951767 DOI: doi:10.1126/sciimmunol.add5446 ]
- Spike glycoprotein (144 kDa, Protein from Severe acute respiratory syndrome coronavirus)
- Three rbd-down state of sars-cov-2 d614g spike in complex with the sp1-77 neutralizing antibody fab fragment (local refinement of the rbd and fab variable domains) (6 MDa, Complex)
- Sp1-77 fab heavy chain (49 kDa, Protein from Homo sapiens)
- Sp1-77 fab light chain (23 kDa, Protein from Homo sapiens)
- Sp1-77 fab heavy chain, sp1-77 fab light chain (Complex from Homo sapiens)
- Spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7upy
Q-score: 0.384
Luo S, Zhang J, Kreutzberger AJB, Eaton A, Edwards RJ, Jing C, Dai HQ, Sempowski GD, Cronin K, Parks R, Ye AY, Mansouri K, Barr M, Pishesha N, Williams AC, Vieira Francisco L, Saminathan A, Peng H, Batra H, Bellusci L, Khurana S, Alam SM, Montefiori DC, Saunders KO, Tian M, Ploegh H, Kirchhausen T, Chen B, Haynes BF, Alt FW
Sci Immunol (2022) 7 pp. eadd5446-eadd5446 [ Pubmed: 35951767 DOI: doi:10.1126/sciimmunol.add5446 ]
- Spike glycoprotein (144 kDa, Protein from Severe acute respiratory syndrome coronavirus)
- Spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus)
- Sp1-77 fab heavy chain (49 kDa, Protein from Homo sapiens)
- Sp1-77 fab light chain (23 kDa, Protein from Homo sapiens)
- Sp1-77 fab heavy chain, sp1-77 fab light chain (Complex from Homo sapiens)
- One rbd-up state of sars-cov-2 d614g spike in complex with the sp1-77 neutralizing antibody fab fragment (650 kDa, Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
G32A4 Fab in complex with SARS-CoV-2 Spike 6P (RBD local reconstruction)
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 7swn
Q-score: 0.358
Windsor IW, Tong P, Lavidor O, Moghaddam AS, McKay LGA, Gautam A, Chen Y, MacDonald EA, Yoo DK, Griffths A, Wesemann DR, Harrison SC
Sci Immunol (2022) 7 pp. eabo3425-eabo3425 [ Pubmed: 35536154 DOI: doi:10.1126/sciimmunol.abo3425 ]
- Spike protein s1 (21 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- C98c7 fab in complex with wt sars-cov-2 rbd (Complex)
- G32a4 fab heavy chain (24 kDa, Protein from Homo sapiens)
- G32a4 fab light chain (23 kDa, Protein from Homo sapiens)
C98C7 Fab in complex with SARS-CoV-2 Spike 6P (RBD local reconstruction)
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 7swo
Q-score: 0.427
Windsor IW, Tong P, Lavidor O, Moghaddam AS, McKay LGA, Gautam A, Chen Y, MacDonald EA, Yoo DK, Griffths A, Wesemann DR, Harrison SC
Sci Immunol (2022) 7 pp. eabo3425-eabo3425 [ Pubmed: 35536154 DOI: doi:10.1126/sciimmunol.abo3425 ]
- C98c7 fab heavy chain (23 kDa, Protein from Homo sapiens)
- Spike protein s1 (21 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- C98c7 fab in complex with wt sars-cov-2 rbd (Complex)
- C98c7 fab light chain (23 kDa, Protein from Homo sapiens)
G32Q4 Fab in complex with SARS-CoV-2 Spike 6P (RBD local reconstruction)
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7swp
Q-score: 0.341
Windsor IW, Tong P, Lavidor O, Moghaddam AS, McKay LGA, Gautam A, Chen Y, MacDonald EA, Yoo DK, Griffths A, Wesemann DR, Harrison SC
Sci Immunol (2022) 7 pp. eabo3425-eabo3425 [ Pubmed: 35536154 DOI: doi:10.1126/sciimmunol.abo3425 ]
- Spike protein s1 (21 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- G32q4 fab heavy chain (25 kDa, Protein from Homo sapiens)
- C98c7 fab in complex with wt sars-cov-2 rbd (Complex from Severe acute respiratory syndrome coronavirus 2)
- G32q4 fab light chain (22 kDa, Protein from Homo sapiens)
Enterovirus D68 in complex with human monoclonal antibody EV68-228
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6wdt
Q-score: 0.589
Vogt MR, Fu J, Kose N, Williamson LE, Bombardi R, Setliff I, Georgiev IS, Klose T, Rossmann MG, Bochkov YA, Gern JE, Kuhn RJ, Crowe Jr JE
Sci Immunol (2020) 5 [ Pubmed: 32620559 DOI: doi:10.1126/sciimmunol.aba4902 ]
- Enterovirus d68 in complex with human monoclonal antibody ev68-228 (Complex)
- Viral protein 1 (32 kDa, Protein from Enterovirus D68)
- Ev68-228 light chain (11 kDa, Protein from Homo sapiens)
- Ev68-228 heavy chain (14 kDa, Protein from Homo sapiens)
- Human monoclonal antibody ev68-228 (Complex from Homo sapiens)
- Viral protein 3 (27 kDa, Protein from Enterovirus D68)
- Viral protein 4 (7 kDa, Protein from Enterovirus D68)
- Enterovirus d68 (Virus from Enterovirus D68)
- Viral protein 2 (27 kDa, Protein from Enterovirus D68)